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Doxifluridine

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Notitia generali
Product name:Doxifluridine
CAS No.:3094-09-5
EINECS login number:221-440-1
forma structuralis
Formulae hypotheticae:C9H11FN2O5
pondus hypotheticum:246.19


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Formulae structurales

11

Corporalis
Species alba solidus
Density:1.3751 (aestima)
18-192 °c(lit.)
Imprimis ROTATIO d25 +18.4° (c = 0.419 In Aqua)
Refractivitas 20 °(c=1, H2o)
Repono Condition inert atmosphaerae, locus Temperature
Acorem Factor(pka):7.4(ad 25℃)

Salus Data
Genus aleam non periculosum bona
Periculo bona traiceret no:
Genus Packaging

Applicationem
1. Prodrug ex 5-Flurouridine.Pyrimidine nucleoside fluorinata cum actione cytostatica.Fusce usus est pro cancer gastricus, cancer colorectalis, cancer pectoris, remissionis rate plus quam 30% attingere potest.
2. Intermedia pro Fluorouracil antitumor medicamentorum

Introductio ad usus
1. Fluorouracil-dicentur procuratores antitumores sunt praecursores ad fluorouracil.phosphorylase enzyme thymidine, quae in tumore textus adest, agit in fluorouracil in tumore convertens, ita anti- tumorem effectum exercens.Fortem anti-tumorem proprietatem habet et toxicitatem humilis.In cancro gastrico, carcinomate colorectali et carcinomate carcinomate usus est, cum remissione rate usque ad 30% vel plus.
2. Pharmaceutical medium.
3. Est agens antitumo, medicamentum praecursoris fluorouracili (5-FU), quod in liberum fluorouracil convertitur, actione pyrimidini nucleosidi phosphorylasi in fibras tumoris, ita inhibens biosynthesin DNA et RNA in cellulis tumore et ostendendo suum effectus antitumour.Cum actio huius enzyme altior est in fibris tumoris quam in fibris normalibus, conversio 5-FU in 5-FU in fibras tumoris celeri et selectiva ad tumores est.Utitur in curatione pectoris, stomachi et carcinomata rectal et toxicity habet humilis.


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